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Original Article
Low levels of tissue inhibitor of metalloproteinase-2 at birth may be associated with subsequent development of bronchopulmonary dysplasia in preterm infants
Choae Lee, Jaewoo An, Ji Hee Kim, Eun Sun Kim, Soo Hyun Kim, Yeon Kyung Cho, Dong Hyun Cha, Man Yong Han, Kyu Hyung Lee, Youn Ho Sheen
Clin Exp Pediatr. 2015;58(11):415-420.   Published online November 22, 2015
Purpose

Bronchopulmonary dysplasia (BPD) is characterized by inflammation with proteolytic damage to the lung extracellular matrix. The results from previous studies are inconsistent regarding the role of proteinases and antiproteinases in the development of BPD. The aim of the present study was to investigate whether matrix metalloproteinase (MMP)-8, MMP-9, tissue inhibitor of metalloproteinase (TIMP)-2, and TIMP-1 levels in the serum of...

Early stress hyperglycemia as independent predictor of increased mortality in preterm infants
Young Sun Wee, Gae Hyun Ahn, Eun Gyong Yoo, In Sook Lim, Kyu Hyung Lee
Clin Exp Pediatr. 2008;51(5):474-480.   Published online May 15, 2008
Purpose : Stress hyperglycemia is common in critically ill adult patients. It is known as a predictor of increased mortality, and intensive insulin therapy has been shown to improve the prognosis in such patients. We have investigated the relationship between early stress hyperglycemia and clinical outcomes in preterm infants. Methods : In this study, 141 preterm infants with a gestational age...
A pilot study of neuroprotection with umbilical cord blood cell transplantation for preterm very low birth weight infants
Kyu Young Chae, Kyu Hyung Lee, So-Hee Eun, Byung Min Choi, Baik-Lin Eun, Hoon-Chul Kang, Myung Jae Chey, Nam Keun Kim, Doyeun Oh
Clin Exp Pediatr. 2007;50(9):882-890.   Published online September 15, 2007
Purpose : Preterm very low birth weight infant have high rate of adverse neurodevelopmental sequale. Recently, there have been lots of reports that human umbilical cord blood transplantation ameliorates functional deficits in animal models as hypoxic ischemic injury. This pilot study was undertaken to determine the clinical efficacy and safety of autologous umbilical cord blood cell transplantation for preventing neurodevelopmental...
Accuracy of References in Journal of the Korean Pediatric Society and Journals of the Korean Pediatric Subspecialty Societies and Citation Pattern Analysis
Gil Ho Cho, Mi Kyung Lee, Man Yong Han, Young Rae Kim, Seo Jung Kim, Kyu Hyung Lee
Clin Exp Pediatr. 2002;45(11):1325-1331.   Published online November 15, 2002
Purpose : We tried to check the accuracy of references in the Journal of the Korean Pediatric Society and Journals of the Korean Pediatric Subspecialty Societies. We also wanted to know the citation patterns of authors by analyzing the frequency of cited materials. Methods : Three journals were randomly selected from the 2000 issues of Journal of the Korean Pediatric Society...
Natural Course of Atrial Septal Defect Diagnosed Within the First 4 Weeks of Life
Young Jun Hwang, Kyung Hyun Chung, Suk Min Choi, Kyu Hyung Lee
Clin Exp Pediatr. 2002;45(5):609-614.   Published online May 15, 2002
Purpose : The purpose of our investigation was to explore the natural course, and the factors that influence the natural course, in ostium secundum atrial septal defect(ASD) diagnosed within the first 4 weeks of life. Methods : We studied patients with ASD diagnosed within the first 4 weeks of life during the period from September 1995 to September 1999 in our...
Study on Closing Time after Indomethacin Administration in Prematurity with Patent Ductus Arteriosus
Wan Cho, Suk Min Choi, Kyu Hyung Lee
Clin Exp Pediatr. 1999;42(11):1508-1515.   Published online November 15, 1999
Purpose : In the clinical field, the closing time of patent ductus arteriosus(PDA) varies among patients after indomethacin administration. We tried to predict it by analyzing related factors, and also by understanding what affects it. Methods : Among 30 cases of PDA at the NICU, 24 cases(male 14 cases, female 10 cases) were selected. Fifteen cases closed early(within 36 hours) and...
Compatibility of Neonatal Parenteral Nutrient Solutions with Commonly Used Drugs during Y-site Delivery in NICU
Ju Hun Choi, Kyong Ju Jeong, Ha Ryung Cho, Dong Soo Yim, Seung Ki Choi, Kyu Hyung Lee
Clin Exp Pediatr. 1998;41(7):893-900.   Published online July 15, 1998
Purpose : Because vascular access sites in neonates are limited, intravenous(IV) medications must often be mixed with maintenance fluids, including parenteral nutrient(PN) solutions. This study was done to determine whether IV medications commonly prescribed in the neonatal in- tensive care unit(NICU) are compatible with the two neonatal PN solutions. Methods : The compatibility of neonatal PN solutions and selected other drugs...
Lipid Profile and Its Association with Coronary Aneurysm in Kawasaki Disease
Ju Sik Choi, Suk Min Choi, Kyu Hyung Lee
Clin Exp Pediatr. 1997;40(6):835-840.   Published online June 15, 1997
Purpose : The value of serum lipid in children after recovery of Kawasaki disease may be important because of the predilection of this disease for the coronary artery. Methods : We measured serum high density lipoprotein(HDL)-cholesterol, total cholesterol, triglycerides in 22 patients (mean age 38months, range 6 to 93 months) with Kawasaki disease during 10 days or less after onset and 2 months later...
Case Report
Dietary Hypocalcemic Tetany.
Kyu Hyung Lee, Chang Bin Im, Yoon Taik Kim, Keun Chan Sohn
Clin Exp Pediatr. 1984;27(5):483-487.   Published online May 31, 1984
Hypocalcemic tetany is important cause of convulsion during perinatal or infantile period. We have experienced three cases of dietary hypocalcemic tetany, which was induced by non-fortified commerical weaning food or breast-fed without vitamine supplement. So we report the cases with review of the related literature.
Original Article
The Statistical Studies on the Emergency Room Patients Under the 15 years of Age.
Kyu Hyung Lee, Sung Ho Cha, Yoon Taik Kim, Don Hee Ahn, Keun Chan Sohn
Clin Exp Pediatr. 1984;27(2):111-121.   Published online February 28, 1984
The studies were carried out to analyze the emergency patient visited to the emergency room of the National Medical Center under the 15 years of during the three-year period from Jan., 1980 to Dec., 1982. The results were obtained as below. 1)During the 3-year periods, the total number of emergency patients under the 15 years of age was 4,212. 2)Forty...
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